L960-1124 Screening compound: 6-(4-fluorophenyl)-2-({5-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1,2,4-oxadiazol-3-yl}methyl)-2,3-dihydropyridazin-3-one

L960-1124 Screening compound: 6-(4-fluorophenyl)-2-({5-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1,2,4-oxadiazol-3-yl}methyl)-2,3-dihydropyridazin-3-one
L960-1124 Screening compound: 6-(4-fluorophenyl)-2-({5-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1,2,4-oxadiazol-3-yl}methyl)-2,3-dihydropyridazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L960-1124
6-(4-fluorophenyl)-2-({5-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1,2,4-oxadiazol-3-yl}methyl)-2,3-dihydropyridazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L960-1124

Molecular Formula

C25H23FN6O4 (C25 H23 FN6 O4)

Compound Name

6-(4-fluorophenyl)-2-({5-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1,2,4-oxadiazol-3-yl}methyl)-2,3-dihydropyridazin-3-one

IUPAC name

6-(4-fluorophenyl)-2-({5-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-124-oxadiazol-3-yl}methyl)-23-dihydropyridazin-3-one

SMILES

COc(cc1)ccc1N(CC1)CCN1C(c1nc(CN(C(C=C2)=O)N=C2c(cc2)ccc2F)no1)=O

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.875

Distribution Coefficient, logD

2.874

Water Solubility, LogSw

-3.14

Polar Surface Area

88.939

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

4.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

L960-1124 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L960-1124 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L960-1124?
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What is the minimum amount of L960-1124 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L960-1124
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L960-1124
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L960-1124 available by request