L960-1131 Screening compound: 3-{[3-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

L960-1131 Screening compound: 3-{[3-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide
L960-1131 Screening compound: 3-{[3-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L960-1131
3-{[3-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L960-1131

Molecular Formula

C22H19FN6O5S (C22 H19 FN6 O5 S)

Compound Name

3-{[3-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

IUPAC name

3-{[3-(4-fluorophenyl)-6-oxo-16-dihydropyridazin-1-yl]methyl}-N-[2-(4-sulfamoylphenyl)ethyl]-124-oxadiazole-5-carboxamide

SMILES

NS(c1ccc(CCNC(c2nc(CN(C(C=C3)=O)N=C3c(cc3)ccc3F)no2)=O)cc1)(=O)=O

InChI

InChI=1S/C22H19FN6O5S/c23-16-5-3-15(4-6-16)18-9-10-20(30)29(27-18)13-19-26-22(34-28-19)21(31)25-12-11-14-1-7-17(8-2-14)35(24,32)33/h1-10H,11-13H2,(H,25,31)(H2,24,32,33)

InChI Key

PZZXDONPLBRUMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27490186

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.49

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

0.843

Distribution Coefficient, logD

0.842

Water Solubility, LogSw

-2.30

Polar Surface Area

136.345

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

0.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

L960-1131 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with L960-1131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L960-1131?
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What is the minimum amount of L960-1131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L960-1131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L960-1131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L960-1131 available by request