L966-0008 Screening compound: N-[(3-methoxyphenyl)methyl]-2-{[4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}acetamide

L966-0008 Screening compound: N-[(3-methoxyphenyl)methyl]-2-{[4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}acetamide
L966-0008 Screening compound: N-[(3-methoxyphenyl)methyl]-2-{[4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L966-0008
N-[(3-methoxyphenyl)methyl]-2-{[4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L966-0008

Molecular Formula

C24H22N4O3S2 (C24 H22 N4 O3 S2)

Compound Name

N-[(3-methoxyphenyl)methyl]-2-{[4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}acetamide

IUPAC name

N-[(3-methoxyphenyl)methyl]-2-{[4-(4-methyl-2-phenyl-13-thiazol-5-yl)-6-oxo-16-dihydropyrimidin-2-yl]sulfanyl}acetamide

SMILES

Cc1c(C(N=C(N2)SCC(NCc3cc(OC)ccc3)=O)=CC2=O)sc(-c2ccccc2)n1

InChI

InChI=1S/C24H22N4O3S2/c1-15-22(33-23(26-15)17-8-4-3-5-9-17)19-12-20(29)28-24(27-19)32-14-21(30)25-13-16-7-6-10-18(11-16)31-2/h3-12H,13-14H2,1-2H3,(H,25,30)(H,27,28,29)

InChI Key

JQJJTDARQIZYQV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15137804

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.898

Distribution Coefficient, logD

3.579

Water Solubility, LogSw

-4.13

Polar Surface Area

76.856

Acid Dissociation Constant (pKa)

7.36

Base Dissociation Constant (pKb)

2.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L966-0008 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L966-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L966-0008?
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What is the minimum amount of L966-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L966-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L966-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L966-0008 available by request