L966-0283 Screening compound: 2-({4-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[(furan-2-yl)methyl]acetamide

L966-0283 Screening compound: 2-({4-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[(furan-2-yl)methyl]acetamide
L966-0283 Screening compound: 2-({4-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[(furan-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L966-0283
2-({4-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[(furan-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L966-0283

Molecular Formula

C21H17ClN4O3S2 (C21 H17 ClN4 O3 S2)

Compound Name

2-({4-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[(furan-2-yl)methyl]acetamide

IUPAC name

2-({4-[2-(4-chlorophenyl)-4-methyl-13-thiazol-5-yl]-6-oxo-16-dihydropyrimidin-2-yl}sulfanyl)-N-[(furan-2-yl)methyl]acetamide

SMILES

Cc1c(C(N=C(N2)SCC(NCc3ccco3)=O)=CC2=O)sc(-c(cc2)ccc2Cl)n1

InChI

InChI=1S/C21H17ClN4O3S2/c1-12-19(31-20(24-12)13-4-6-14(22)7-5-13)16-9-17(27)26-21(25-16)30-11-18(28)23-10-15-3-2-8-29-15/h2-9H,10-11H2,1H3,(H,23,28)(H,25,26,27)

InChI Key

CLHFEVYTVFYHQK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15137841

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.98

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.252

Distribution Coefficient, logD

3.932

Water Solubility, LogSw

-4.58

Polar Surface Area

77.061

Acid Dissociation Constant (pKa)

7.36

Base Dissociation Constant (pKb)

2.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L966-0283 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L966-0283 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L966-0283?
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What is the minimum amount of L966-0283 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L966-0283
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L966-0283
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L966-0283 available by request