L967-0606 Screening compound: ethyl 4-[(2-chloro-5-fluorophenyl)amino]-7-methyl-1,8-naphthyridine-3-carboxylate
Chemical Structure Depiction of ChemDiv screening compound L967-0606
ethyl 4-[(2-chloro-5-fluorophenyl)amino]-7-methyl-1,8-naphthyridine-3-carboxylate
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L967-0606
Molecular Formula
C18H15ClFN3O2 (C18 H15 ClFN3 O2)
Compound Name
ethyl 4-[(2-chloro-5-fluorophenyl)amino]-7-methyl-1,8-naphthyridine-3-carboxylate
IUPAC name
ethyl 4-[(2-chloro-5-fluorophenyl)amino]-7-methyl-18-naphthyridine-3-carboxylate
SMILES
CCOC(c(cnc1nc(C)ccc11)c1Nc(cc(cc1)F)c1Cl)=O
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
HCl
Molecular Weight
359.79
Hydrogen Bond Acceptors Count
5.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
5.00
Number of Nitrogen and Oxygen Atoms
5
Partition Coefficient, logP
4.754
Distribution Coefficient, logD
4.753
Water Solubility, LogSw
-4.89
Polar Surface Area
46.412
Acid Dissociation Constant (pKa)
12.08
Base Dissociation Constant (pKb)
4.48
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
16.70
L967-0606 in Drug Discovery
Included in Screening Libraries
PI3K-Targeted Library (17255 compounds)
SmartTM Library (51161 compounds)
Included in 1.7M Stock Database
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Male
- Female
- Hemic and lymphatic
- Skin
- Kinases
References: we are preparing a list of scientific research reports with L967-0606 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)