L967-1191 Screening compound: propan-2-yl 7-methyl-4-{[4-(trifluoromethoxy)phenyl]amino}-1,8-naphthyridine-3-carboxylate

L967-1191 Screening compound: propan-2-yl 7-methyl-4-{[4-(trifluoromethoxy)phenyl]amino}-1,8-naphthyridine-3-carboxylate
L967-1191 Screening compound: propan-2-yl 7-methyl-4-{[4-(trifluoromethoxy)phenyl]amino}-1,8-naphthyridine-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L967-1191
propan-2-yl 7-methyl-4-{[4-(trifluoromethoxy)phenyl]amino}-1,8-naphthyridine-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L967-1191

Molecular Formula

C20H18F3N3O3 (C20 H18 F3 N3 O3)

Compound Name

propan-2-yl 7-methyl-4-{[4-(trifluoromethoxy)phenyl]amino}-1,8-naphthyridine-3-carboxylate

IUPAC name

propan-2-yl 7-methyl-4-{[4-(trifluoromethoxy)phenyl]amino}-18-naphthyridine-3-carboxylate

SMILES

CC(C)OC(c(cnc1nc(C)ccc11)c1Nc(cc1)ccc1OC(F)(F)F)=O

InChI

InChI=1S/C20H18F3N3O3/c1-11(2)28-19(27)16-10-24-18-15(9-4-12(3)25-18)17(16)26-13-5-7-14(8-6-13)29-20(21,22)23/h4-11H,1-3H3,(H,24,25,26)

InChI Key

ISAUFFXFFNITDV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22591052

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

405.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.401

Distribution Coefficient, logD

5.401

Water Solubility, LogSw

-5.46

Polar Surface Area

52.725

Acid Dissociation Constant (pKa)

15.51

Base Dissociation Constant (pKb)

4.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L967-1191 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L967-1191 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L967-1191?
Check Price and Availability of L967-1191, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L967-1191 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L967-1191
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L967-1191
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L967-1191 available by request