M008-0128 Screening compound: 5-bromo-N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]pyridin-2-amine

M008-0128 Screening compound: 5-bromo-N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]pyridin-2-amine
M008-0128 Screening compound: 5-bromo-N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]pyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M008-0128
5-bromo-N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]pyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M008-0128

Molecular Formula

C16H14BrN3O2S (C16 H14 BrN3 O2 S)

Compound Name

5-bromo-N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]pyridin-2-amine

IUPAC name

5-bromo-N-[4-(34-dimethoxyphenyl)-13-thiazol-2-yl]pyridin-2-amine

SMILES

COc(ccc(-c1csc(Nc(cc2)ncc2Br)n1)c1)c1OC

InChI

InChI=1S/C16H14BrN3O2S/c1-21-13-5-3-10(7-14(13)22-2)12-9-23-16(19-12)20-15-6-4-11(17)8-18-15/h3-9H,1-2H3,(H,18,19,20)

InChI Key

PUQPLFAALLQBTO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22591676

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.28

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.242

Distribution Coefficient, logD

5.240

Water Solubility, LogSw

-5.13

Polar Surface Area

43.891

Acid Dissociation Constant (pKa)

16.96

Base Dissociation Constant (pKb)

5.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

M008-0128 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Proteases
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M008-0128 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M008-0128?
Check Price and Availability of M008-0128, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M008-0128 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M008-0128
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M008-0128
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M008-0128 available by request