M008-1630 Screening compound: 1'-({2-[(5-fluoropyridin-2-yl)amino]-4-methyl-1,3-thiazol-5-yl}carbonyl)-1,4'-bipiperidine-4'-carboxamide

M008-1630 Screening compound: 1'-({2-[(5-fluoropyridin-2-yl)amino]-4-methyl-1,3-thiazol-5-yl}carbonyl)-1,4'-bipiperidine-4'-carboxamide
M008-1630 Screening compound: 1'-({2-[(5-fluoropyridin-2-yl)amino]-4-methyl-1,3-thiazol-5-yl}carbonyl)-1,4'-bipiperidine-4'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M008-1630
1'-({2-[(5-fluoropyridin-2-yl)amino]-4-methyl-1,3-thiazol-5-yl}carbonyl)-1,4'-bipiperidine-4'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M008-1630

Molecular Formula

C21H27FN6O2S (C21 H27 FN6 O2 S)

Compound Name

1'-({2-[(5-fluoropyridin-2-yl)amino]-4-methyl-1,3-thiazol-5-yl}carbonyl)-1,4'-bipiperidine-4'-carboxamide

IUPAC name

n/a

SMILES

Cc1c(C(N(CC2)CCC2(C(N)=O)N2CCCCC2)=O)sc(Nc(cc2)ncc2F)n1

InChI

InChI=1S/C21H27FN6O2S/c1-14-17(31-20(25-14)26-16-6-5-15(22)13-24-16)18(29)27-11-7-21(8-12-27,19(23)30)28-9-3-2-4-10-28/h5-6,13H,2-4,7-12H2,1H3,(H2,23,30)(H,24,25,26)

InChI Key

SJPYRKXZJQFSJB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27491818

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.172

Distribution Coefficient, logD

2.098

Water Solubility, LogSw

-3.26

Polar Surface Area

83.263

Acid Dissociation Constant (pKa)

13.93

Base Dissociation Constant (pKb)

8.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.40

M008-1630 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M008-1630 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M008-1630?
Check Price and Availability of M008-1630, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M008-1630 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M008-1630
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M008-1630
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M008-1630 available by request