M008-1646 Screening compound: N-{5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-4-methyl-1,3-thiazol-2-yl}-5-fluoropyridin-2-amine

M008-1646 Screening compound: N-{5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-4-methyl-1,3-thiazol-2-yl}-5-fluoropyridin-2-amine
M008-1646 Screening compound: N-{5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-4-methyl-1,3-thiazol-2-yl}-5-fluoropyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M008-1646
N-{5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-4-methyl-1,3-thiazol-2-yl}-5-fluoropyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M008-1646

Molecular Formula

C22H24FN5OS (C22 H24 FN5 OS)

Compound Name

N-{5-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-4-methyl-1,3-thiazol-2-yl}-5-fluoropyridin-2-amine

IUPAC name

N-{5-[4-(23-dimethylphenyl)piperazine-1-carbonyl]-4-methyl-13-thiazol-2-yl}-5-fluoropyridin-2-amine

SMILES

Cc1c(C(N(CC2)CCN2c2c(C)c(C)ccc2)=O)sc(Nc(cc2)ncc2F)n1

InChI

InChI=1S/C22H24FN5OS/c1-14-5-4-6-18(15(14)2)27-9-11-28(12-10-27)21(29)20-16(3)25-22(30-20)26-19-8-7-17(23)13-24-19/h4-8,13H,9-12H2,1-3H3,(H,24,25,26)

InChI Key

PBWDWSATGFLPMR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27491822

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.440

Distribution Coefficient, logD

5.436

Water Solubility, LogSw

-5.28

Polar Surface Area

49.086

Acid Dissociation Constant (pKa)

13.93

Base Dissociation Constant (pKb)

5.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

M008-1646 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with M008-1646 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M008-1646?
Check Price and Availability of M008-1646, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M008-1646 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M008-1646
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M008-1646
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M008-1646 available by request