M008-4731 Screening compound: 4-methyl-2-[(4-methylpyridin-2-yl)amino]-N-[2-(morpholin-4-yl)ethyl]-1,3-thiazole-5-carboxamide

M008-4731 Screening compound: 4-methyl-2-[(4-methylpyridin-2-yl)amino]-N-[2-(morpholin-4-yl)ethyl]-1,3-thiazole-5-carboxamide
M008-4731 Screening compound: 4-methyl-2-[(4-methylpyridin-2-yl)amino]-N-[2-(morpholin-4-yl)ethyl]-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M008-4731
4-methyl-2-[(4-methylpyridin-2-yl)amino]-N-[2-(morpholin-4-yl)ethyl]-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M008-4731

Molecular Formula

C17H23N5O2S (C17 H23 N5 O2 S)

Compound Name

4-methyl-2-[(4-methylpyridin-2-yl)amino]-N-[2-(morpholin-4-yl)ethyl]-1,3-thiazole-5-carboxamide

IUPAC name

4-methyl-2-[(4-methylpyridin-2-yl)amino]-N-[2-(morpholin-4-yl)ethyl]-13-thiazole-5-carboxamide

SMILES

Cc1c(C(NCCN2CCOCC2)=O)sc(Nc2nccc(C)c2)n1

InChI

InChI=1S/C17H23N5O2S/c1-12-3-4-18-14(11-12)21-17-20-13(2)15(25-17)16(23)19-5-6-22-7-9-24-10-8-22/h3-4,11H,5-10H2,1-2H3,(H,19,23)(H,18,20,21)

InChI Key

BFWZZBGPWFOFSW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27491900

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.988

Distribution Coefficient, logD

1.363

Water Solubility, LogSw

-2.64

Polar Surface Area

65.535

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

7.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.10

M008-4731 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M008-4731 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M008-4731?
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What is the minimum amount of M008-4731 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M008-4731
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M008-4731
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M008-4731 available by request