M008-5222 Screening compound: N-(1-BENZYLPIPERIDIN-4-YL)-4-METHYL-2-[(6-METHYLPYRIDIN-2-YL)AMINO]-1,3-THIAZOLE-5-CARBOXAMIDE

M008-5222 Screening compound: N-(1-BENZYLPIPERIDIN-4-YL)-4-METHYL-2-[(6-METHYLPYRIDIN-2-YL)AMINO]-1,3-THIAZOLE-5-CARBOXAMIDE
M008-5222 Screening compound: N-(1-BENZYLPIPERIDIN-4-YL)-4-METHYL-2-[(6-METHYLPYRIDIN-2-YL)AMINO]-1,3-THIAZOLE-5-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound M008-5222
N-(1-BENZYLPIPERIDIN-4-YL)-4-METHYL-2-[(6-METHYLPYRIDIN-2-YL)AMINO]-1,3-THIAZOLE-5-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M008-5222

Molecular Formula

C23H27N5OS (C23 H27 N5 OS)

Compound Name

N-(1-BENZYLPIPERIDIN-4-YL)-4-METHYL-2-[(6-METHYLPYRIDIN-2-YL)AMINO]-1,3-THIAZOLE-5-CARBOXAMIDE

IUPAC name

n/a

SMILES

Cc1c(C(NC2CCN(Cc3ccccc3)CC2)=O)sc(Nc2nc(C)ccc2)n1

InChI

InChI=1S/C23H27N5OS/c1-16-7-6-10-20(24-16)27-23-25-17(2)21(30-23)22(29)26-19-11-13-28(14-12-19)15-18-8-4-3-5-9-18/h3-10,19H,11-15H2,1-2H3,(H,26,29)(H,24,25,27)

InChI Key

RVERPSJCPIINSM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27491923

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.343

Distribution Coefficient, logD

2.898

Water Solubility, LogSw

-4.16

Polar Surface Area

56.443

Acid Dissociation Constant (pKa)

14.49

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

M008-5222 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M008-5222 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M008-5222?
Check Price and Availability of M008-5222, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M008-5222 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M008-5222
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M008-5222
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M008-5222 available by request