M022-1143 Screening compound: 4-(4,5-dimethyl-1,3-thiazol-2-yl)-N-{[4-(piperidin-1-yl)phenyl]methyl}thiophene-2-sulfonamide

M022-1143 Screening compound: 4-(4,5-dimethyl-1,3-thiazol-2-yl)-N-{[4-(piperidin-1-yl)phenyl]methyl}thiophene-2-sulfonamide
M022-1143 Screening compound: 4-(4,5-dimethyl-1,3-thiazol-2-yl)-N-{[4-(piperidin-1-yl)phenyl]methyl}thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M022-1143
4-(4,5-dimethyl-1,3-thiazol-2-yl)-N-{[4-(piperidin-1-yl)phenyl]methyl}thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M022-1143

Molecular Formula

C21H25N3O2S3 (C21 H25 N3 O2 S3)

Compound Name

4-(4,5-dimethyl-1,3-thiazol-2-yl)-N-{[4-(piperidin-1-yl)phenyl]methyl}thiophene-2-sulfonamide

IUPAC name

4-(45-dimethyl-13-thiazol-2-yl)-N-{[4-(piperidin-1-yl)phenyl]methyl}thiophene-2-sulfonamide

SMILES

Cc1c(C)sc(-c2csc(S(NCc(cc3)ccc3N3CCCCC3)(=O)=O)c2)n1

InChI

InChI=1S/C21H25N3O2S3/c1-15-16(2)28-21(23-15)18-12-20(27-14-18)29(25,26)22-13-17-6-8-19(9-7-17)24-10-4-3-5-11-24/h6-9,12,14,22H,3-5,10-11,13H2,1-2H3

InChI Key

RFLIKUJVLYZPTE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27493025

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.65

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.927

Distribution Coefficient, logD

4.904

Water Solubility, LogSw

-4.62

Polar Surface Area

56.778

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

6.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

M022-1143 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M022-1143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M022-1143?
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What is the minimum amount of M022-1143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M022-1143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M022-1143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M022-1143 available by request