M022-1525 Screening compound: N-[(3,5-difluorophenyl)methyl]-4-[4-(2-methylpropyl)-1,3-thiazol-2-yl]thiophene-2-sulfonamide

M022-1525 Screening compound: N-[(3,5-difluorophenyl)methyl]-4-[4-(2-methylpropyl)-1,3-thiazol-2-yl]thiophene-2-sulfonamide
M022-1525 Screening compound: N-[(3,5-difluorophenyl)methyl]-4-[4-(2-methylpropyl)-1,3-thiazol-2-yl]thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M022-1525
N-[(3,5-difluorophenyl)methyl]-4-[4-(2-methylpropyl)-1,3-thiazol-2-yl]thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M022-1525

Molecular Formula

C18H18F2N2O2S3 (C18 H18 F2 N2 O2 S3)

Compound Name

N-[(3,5-difluorophenyl)methyl]-4-[4-(2-methylpropyl)-1,3-thiazol-2-yl]thiophene-2-sulfonamide

IUPAC name

N-[(35-difluorophenyl)methyl]-4-[4-(2-methylpropyl)-13-thiazol-2-yl]thiophene-2-sulfonamide

SMILES

CC(C)Cc1csc(-c2csc(S(NCc3cc(F)cc(F)c3)(=O)=O)c2)n1

InChI

InChI=1S/C18H18F2N2O2S3/c1-11(2)3-16-10-26-18(22-16)13-6-17(25-9-13)27(23,24)21-8-12-4-14(19)7-15(20)5-12/h4-7,9-11,21H,3,8H2,1-2H3

InChI Key

IUAIIWJZDJATIH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27493075

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.729

Distribution Coefficient, logD

5.727

Water Solubility, LogSw

-5.51

Polar Surface Area

53.244

Acid Dissociation Constant (pKa)

9.65

Base Dissociation Constant (pKb)

2.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

M022-1525 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M022-1525 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M022-1525?
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What is the minimum amount of M022-1525 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M022-1525
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M022-1525
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M022-1525 available by request