M022-1724 Screening compound: 4-(4-tert-butyl-1,3-thiazol-2-yl)-N-(3-chloro-4-methoxyphenyl)thiophene-2-sulfonamide

M022-1724 Screening compound: 4-(4-tert-butyl-1,3-thiazol-2-yl)-N-(3-chloro-4-methoxyphenyl)thiophene-2-sulfonamide
M022-1724 Screening compound: 4-(4-tert-butyl-1,3-thiazol-2-yl)-N-(3-chloro-4-methoxyphenyl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M022-1724
4-(4-tert-butyl-1,3-thiazol-2-yl)-N-(3-chloro-4-methoxyphenyl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M022-1724

Molecular Formula

C18H19ClN2O3S3 (C18 H19 ClN2 O3 S3)

Compound Name

4-(4-tert-butyl-1,3-thiazol-2-yl)-N-(3-chloro-4-methoxyphenyl)thiophene-2-sulfonamide

IUPAC name

4-(4-tert-butyl-13-thiazol-2-yl)-N-(3-chloro-4-methoxyphenyl)thiophene-2-sulfonamide

SMILES

CC(C)(C)c1csc(-c2csc(S(Nc(cc3)cc(Cl)c3OC)(=O)=O)c2)n1

InChI

InChI=1S/C18H19ClN2O3S3/c1-18(2,3)15-10-26-17(20-15)11-7-16(25-9-11)27(22,23)21-12-5-6-14(24-4)13(19)8-12/h5-10,21H,1-4H3

InChI Key

GDMJUZRNANYSSQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27493122

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.01

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.883

Distribution Coefficient, logD

5.640

Water Solubility, LogSw

-6.20

Polar Surface Area

59.271

Acid Dissociation Constant (pKa)

7.53

Base Dissociation Constant (pKb)

3.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

M022-1724 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M022-1724 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M022-1724?
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What is the minimum amount of M022-1724 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M022-1724
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M022-1724
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M022-1724 available by request