M040-0372 Screening compound: 3-(2,4-dimethoxyphenyl)-5-{[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]methyl}-1,2,4-oxadiazole

M040-0372 Screening compound: 3-(2,4-dimethoxyphenyl)-5-{[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]methyl}-1,2,4-oxadiazole
M040-0372 Screening compound: 3-(2,4-dimethoxyphenyl)-5-{[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]methyl}-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound M040-0372
3-(2,4-dimethoxyphenyl)-5-{[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]methyl}-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M040-0372

Molecular Formula

C22H21N3O4S (C22 H21 N3 O4 S)

Compound Name

3-(2,4-dimethoxyphenyl)-5-{[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]methyl}-1,2,4-oxadiazole

IUPAC name

3-(24-dimethoxyphenyl)-5-{[4-(4-ethoxyphenyl)-13-thiazol-2-yl]methyl}-124-oxadiazole

SMILES

CCOc(cc1)ccc1-c1csc(Cc2nc(-c(ccc(OC)c3)c3OC)no2)n1

InChI

InChI=1S/C22H21N3O4S/c1-4-28-15-7-5-14(6-8-15)18-13-30-21(23-18)12-20-24-22(25-29-20)17-10-9-16(26-2)11-19(17)27-3/h5-11,13H,4,12H2,1-3H3

InChI Key

MFGOKJTVLCUYIR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27494197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.620

Distribution Coefficient, logD

5.620

Water Solubility, LogSw

-5.57

Polar Surface Area

63.837

Acid Dissociation Constant (pKa)

29.85

Base Dissociation Constant (pKb)

1.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

M040-0372 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M040-0372 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M040-0372?
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What is the minimum amount of M040-0372 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M040-0372
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M040-0372
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M040-0372 available by request