M061-0427 Screening compound: N-(4-acetylphenyl)-5,7-dimethyl-3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

M061-0427 Screening compound: N-(4-acetylphenyl)-5,7-dimethyl-3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
M061-0427 Screening compound: N-(4-acetylphenyl)-5,7-dimethyl-3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M061-0427
N-(4-acetylphenyl)-5,7-dimethyl-3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M061-0427

Molecular Formula

C29H31N5O4S (C29 H31 N5 O4 S)

Compound Name

N-(4-acetylphenyl)-5,7-dimethyl-3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

N-(4-acetylphenyl)-57-dimethyl-3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

CC(c(cc1)ccc1NC(c1nn2c(C)cc(C)nc2c1-c1cc(S(N2CCCCC2)(=O)=O)c(C)cc1)=O)=O

InChI

InChI=1S/C29H31N5O4S/c1-18-8-9-23(17-25(18)39(37,38)33-14-6-5-7-15-33)26-27(32-34-20(3)16-19(2)30-28(26)34)29(36)31-24-12-10-22(11-13-24)21(4)35/h8-13,16-17H,5-7,14-15H2,1-4H3,(H,31,36)

InChI Key

XJCZJGBFIQVJDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27495270

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

545.66

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.882

Distribution Coefficient, logD

3.882

Water Solubility, LogSw

-4.01

Polar Surface Area

89.120

Acid Dissociation Constant (pKa)

11.12

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.00

M061-0427 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Lipid Metabolism Library (9174 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with M061-0427 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M061-0427?
Check Price and Availability of M061-0427, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M061-0427 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M061-0427
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M061-0427
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M061-0427 available by request