M074-0530 Screening compound: (2E)-N-(1-ethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-3-(4-methylphenyl)prop-2-enamide

M074-0530 Screening compound: (2E)-N-(1-ethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-3-(4-methylphenyl)prop-2-enamide
M074-0530 Screening compound: (2E)-N-(1-ethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-3-(4-methylphenyl)prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M074-0530
(2E)-N-(1-ethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-3-(4-methylphenyl)prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M074-0530

Molecular Formula

C21H22N2O2 (C21 H22 N2 O2)

Compound Name

(2E)-N-(1-ethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-3-(4-methylphenyl)prop-2-enamide

IUPAC name

(2E)-N-(1-ethyl-2-oxo-1234-tetrahydroquinolin-6-yl)-3-(4-methylphenyl)prop-2-enamide

SMILES

CCN(C(CC1)=O)c(cc2)c1cc2NC(/C=C/c1ccc(C)cc1)=O

InChI

InChI=1S/C21H22N2O2/c1-3-23-19-11-10-18(14-17(19)9-13-21(23)25)22-20(24)12-8-16-6-4-15(2)5-7-16/h4-8,10-12,14H,3,9,13H2,1-2H3,(H,22,24)

InChI Key

IXJHEPHRGFEPFI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27643813

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

334.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.362

Distribution Coefficient, logD

4.362

Water Solubility, LogSw

-4.28

Polar Surface Area

38.493

Acid Dissociation Constant (pKa)

12.39

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

M074-0530 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with M074-0530 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M074-0530?
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What is the minimum amount of M074-0530 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M074-0530
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M074-0530
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M074-0530 available by request