M077-0196 Screening compound: 1-{1-ethyl-3-methyl-1H-pyrazolo[3,4-c]pyridin-7-yl}-N-{[4-(morpholin-4-yl)phenyl]methyl}piperidine-4-carboxamide

M077-0196 Screening compound: 1-{1-ethyl-3-methyl-1H-pyrazolo[3,4-c]pyridin-7-yl}-N-{[4-(morpholin-4-yl)phenyl]methyl}piperidine-4-carboxamide
M077-0196 Screening compound: 1-{1-ethyl-3-methyl-1H-pyrazolo[3,4-c]pyridin-7-yl}-N-{[4-(morpholin-4-yl)phenyl]methyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M077-0196
1-{1-ethyl-3-methyl-1H-pyrazolo[3,4-c]pyridin-7-yl}-N-{[4-(morpholin-4-yl)phenyl]methyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M077-0196

Molecular Formula

C26H34N6O2 (C26 H34 N6 O2)

Compound Name

1-{1-ethyl-3-methyl-1H-pyrazolo[3,4-c]pyridin-7-yl}-N-{[4-(morpholin-4-yl)phenyl]methyl}piperidine-4-carboxamide

IUPAC name

1-{1-ethyl-3-methyl-1H-pyrazolo[34-c]pyridin-7-yl}-N-{[4-(morpholin-4-yl)phenyl]methyl}piperidine-4-carboxamide

SMILES

CCn1nc(C)c2c1c(N(CC1)CCC1C(NCc(cc1)ccc1N1CCOCC1)=O)ncc2

InChI

InChI=1S/C26H34N6O2/c1-3-32-24-23(19(2)29-32)8-11-27-25(24)31-12-9-21(10-13-31)26(33)28-18-20-4-6-22(7-5-20)30-14-16-34-17-15-30/h4-8,11,21H,3,9-10,12-18H2,1-2H3,(H,28,33)

InChI Key

YBOZSXSEVWZBLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27496416

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.348

Distribution Coefficient, logD

2.283

Water Solubility, LogSw

-2.64

Polar Surface Area

62.003

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

6.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

M077-0196 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M077-0196 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M077-0196?
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What is the minimum amount of M077-0196 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M077-0196
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M077-0196
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M077-0196 available by request