M089-0148 Screening compound: 1-(4-fluorophenyl)-4-({2-methyl-5-[5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-3-yl}sulfonyl)piperazine

M089-0148 Screening compound: 1-(4-fluorophenyl)-4-({2-methyl-5-[5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-3-yl}sulfonyl)piperazine
M089-0148 Screening compound: 1-(4-fluorophenyl)-4-({2-methyl-5-[5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-3-yl}sulfonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound M089-0148
1-(4-fluorophenyl)-4-({2-methyl-5-[5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-3-yl}sulfonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M089-0148

Molecular Formula

C19H18F4N4O2S2 (C19 H18 F4 N4 O2 S2)

Compound Name

1-(4-fluorophenyl)-4-({2-methyl-5-[5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-3-yl}sulfonyl)piperazine

IUPAC name

1-(4-fluorophenyl)-4-({2-methyl-5-[5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-3-yl}sulfonyl)piperazine

SMILES

Cc(sc(-c1n[nH]c(C(F)(F)F)c1)c1)c1S(N(CC1)CCN1c(cc1)ccc1F)(=O)=O

InChI

InChI=1S/C19H18F4N4O2S2/c1-12-17(11-16(30-12)15-10-18(25-24-15)19(21,22)23)31(28,29)27-8-6-26(7-9-27)14-4-2-13(20)3-5-14/h2-5,10-11H,6-9H2,1H3,(H,24,25)

InChI Key

QMCLVPSPAIBCMK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27496581

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.635

Distribution Coefficient, logD

4.628

Water Solubility, LogSw

-4.38

Polar Surface Area

58.718

Acid Dissociation Constant (pKa)

5.70

Base Dissociation Constant (pKb)

5.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

M089-0148 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M089-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M089-0148?
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What is the minimum amount of M089-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M089-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M089-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M089-0148 available by request