M108-0126 Screening compound: 6-[2-(6-methyl-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-2-oxoethyl]-3-(4-methylphenyl)-6H,7H-[1,2]thiazolo[4,5-d]pyrimidin-7-one

M108-0126 Screening compound: 6-[2-(6-methyl-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-2-oxoethyl]-3-(4-methylphenyl)-6H,7H-[1,2]thiazolo[4,5-d]pyrimidin-7-one
M108-0126 Screening compound: 6-[2-(6-methyl-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-2-oxoethyl]-3-(4-methylphenyl)-6H,7H-[1,2]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M108-0126
6-[2-(6-methyl-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-2-oxoethyl]-3-(4-methylphenyl)-6H,7H-[1,2]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M108-0126

Molecular Formula

C23H20N4O3S (C23 H20 N4 O3 S)

Compound Name

6-[2-(6-methyl-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-2-oxoethyl]-3-(4-methylphenyl)-6H,7H-[1,2]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

6-[2-(6-methyl-34-dihydro-2H-14-benzoxazin-4-yl)-2-oxoethyl]-3-(4-methylphenyl)-6H7H-[12]thiazolo[45-d]pyrimidin-7-one

SMILES

Cc(cc1)ccc1-c1nsc2c1N=CN(CC(N1c(cc(C)cc3)c3OCC1)=O)C2=O

InChI

InChI=1S/C23H20N4O3S/c1-14-3-6-16(7-4-14)20-21-22(31-25-20)23(29)26(13-24-21)12-19(28)27-9-10-30-18-8-5-15(2)11-17(18)27/h3-8,11,13H,9-10,12H2,1-2H3

InChI Key

DHYAWCRGFPSAJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27497183

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.339

Distribution Coefficient, logD

3.339

Water Solubility, LogSw

-3.62

Polar Surface Area

58.085

Acid Dissociation Constant (pKa)

25.05

Base Dissociation Constant (pKb)

-0.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

M108-0126 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M108-0126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M108-0126?
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What is the minimum amount of M108-0126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M108-0126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M108-0126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M108-0126 available by request