M124-0172 Screening compound: methyl 2-(4-carbamoylpiperidin-1-yl)-4-oxo-3-(2-phenylethyl)-3,4-dihydroquinazoline-7-carboxylate

M124-0172 Screening compound: methyl 2-(4-carbamoylpiperidin-1-yl)-4-oxo-3-(2-phenylethyl)-3,4-dihydroquinazoline-7-carboxylate
M124-0172 Screening compound: methyl 2-(4-carbamoylpiperidin-1-yl)-4-oxo-3-(2-phenylethyl)-3,4-dihydroquinazoline-7-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound M124-0172
methyl 2-(4-carbamoylpiperidin-1-yl)-4-oxo-3-(2-phenylethyl)-3,4-dihydroquinazoline-7-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M124-0172

Molecular Formula

C24H26N4O4 (C24 H26 N4 O4)

Compound Name

methyl 2-(4-carbamoylpiperidin-1-yl)-4-oxo-3-(2-phenylethyl)-3,4-dihydroquinazoline-7-carboxylate

IUPAC name

methyl 2-(4-carbamoylpiperidin-1-yl)-4-oxo-3-(2-phenylethyl)-34-dihydroquinazoline-7-carboxylate

SMILES

COC(c(cc1)cc(N=C(N2CCc3ccccc3)N(CC3)CCC3C(N)=O)c1C2=O)=O

InChI

InChI=1S/C24H26N4O4/c1-32-23(31)18-7-8-19-20(15-18)26-24(27-12-10-17(11-13-27)21(25)29)28(22(19)30)14-9-16-5-3-2-4-6-16/h2-8,15,17H,9-14H2,1H3,(H2,25,29)

InChI Key

WXFLAJJSJHBVBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498244

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.342

Distribution Coefficient, logD

2.342

Water Solubility, LogSw

-2.94

Polar Surface Area

84.034

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

4.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

M124-0172 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M124-0172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M124-0172?
Check Price and Availability of M124-0172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M124-0172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M124-0172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M124-0172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M124-0172 available by request