M124-0681 Screening compound: methyl 3-(3,5-dimethylphenyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-oxo-3,4-dihydroquinazoline-7-carboxylate

M124-0681 Screening compound: methyl 3-(3,5-dimethylphenyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-oxo-3,4-dihydroquinazoline-7-carboxylate
M124-0681 Screening compound: methyl 3-(3,5-dimethylphenyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-oxo-3,4-dihydroquinazoline-7-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound M124-0681
methyl 3-(3,5-dimethylphenyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-oxo-3,4-dihydroquinazoline-7-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M124-0681

Molecular Formula

C29H30N4O4 (C29 H30 N4 O4)

Compound Name

methyl 3-(3,5-dimethylphenyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-oxo-3,4-dihydroquinazoline-7-carboxylate

IUPAC name

methyl 3-(35-dimethylphenyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-oxo-34-dihydroquinazoline-7-carboxylate

SMILES

Cc1cc(N2C(N(CC3)CCN3c(cccc3)c3OC)=Nc(cc(cc3)C(OC)=O)c3C2=O)cc(C)c1

InChI

InChI=1S/C29H30N4O4/c1-19-15-20(2)17-22(16-19)33-27(34)23-10-9-21(28(35)37-4)18-24(23)30-29(33)32-13-11-31(12-14-32)25-7-5-6-8-26(25)36-3/h5-10,15-18H,11-14H2,1-4H3

InChI Key

YJKKWBSAHSSFOC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498391

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.943

Distribution Coefficient, logD

4.935

Water Solubility, LogSw

-4.65

Polar Surface Area

59.975

Acid Dissociation Constant (pKa)

28.55

Base Dissociation Constant (pKb)

5.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.60

M124-0681 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with M124-0681 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M124-0681?
Check Price and Availability of M124-0681, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M124-0681 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M124-0681
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M124-0681
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M124-0681 available by request