M127-0578 Screening compound: N-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

M127-0578 Screening compound: N-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide
M127-0578 Screening compound: N-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M127-0578
N-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M127-0578

Molecular Formula

C20H12ClF2N3O (C20 H12 ClF2 N3 O)

Compound Name

N-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

IUPAC name

N-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)-1H-indazole-3-carboxamide

SMILES

O=C(c(c1c2cccc1)nn2-c(cc1)ccc1F)Nc(ccc(F)c1)c1Cl

InChI

InChI=1S/C20H12ClF2N3O/c21-16-11-13(23)7-10-17(16)24-20(27)19-15-3-1-2-4-18(15)26(25-19)14-8-5-12(22)6-9-14/h1-11H,(H,24,27)

InChI Key

RCNLCGGTMHQPIA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498481

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.78

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.114

Distribution Coefficient, logD

5.113

Water Solubility, LogSw

-5.72

Polar Surface Area

36.746

Acid Dissociation Constant (pKa)

10.32

Base Dissociation Constant (pKb)

-3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

M127-0578 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M127-0578 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M127-0578?
Check Price and Availability of M127-0578, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M127-0578 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M127-0578
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M127-0578
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M127-0578 available by request