M130-0492 Screening compound: 3-(2-methoxyphenyl)-1-{4-[6-(2-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}propan-1-one

M130-0492 Screening compound: 3-(2-methoxyphenyl)-1-{4-[6-(2-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}propan-1-one
M130-0492 Screening compound: 3-(2-methoxyphenyl)-1-{4-[6-(2-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M130-0492
3-(2-methoxyphenyl)-1-{4-[6-(2-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M130-0492

Molecular Formula

C25H28N4O2 (C25 H28 N4 O2)

Compound Name

3-(2-methoxyphenyl)-1-{4-[6-(2-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}propan-1-one

IUPAC name

3-(2-methoxyphenyl)-1-{4-[6-(2-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}propan-1-one

SMILES

Cc(cccc1)c1-c1cc(N(CC2)CCN2C(CCc(cccc2)c2OC)=O)ncn1

InChI

InChI=1S/C25H28N4O2/c1-19-7-3-5-9-21(19)22-17-24(27-18-26-22)28-13-15-29(16-14-28)25(30)12-11-20-8-4-6-10-23(20)31-2/h3-10,17-18H,11-16H2,1-2H3

InChI Key

KHQFVGBFMKOMTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498533

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.624

Distribution Coefficient, logD

4.624

Water Solubility, LogSw

-4.46

Polar Surface Area

46.252

Acid Dissociation Constant (pKa)

23.24

Base Dissociation Constant (pKb)

4.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

M130-0492 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

Akt-Targeted Library (14764 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Kinases
  • Others
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M130-0492 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M130-0492?
Check Price and Availability of M130-0492, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M130-0492 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M130-0492
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M130-0492
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M130-0492 available by request