M130-1090 Screening compound: (2E)-1-{4-[6-(4-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

M130-1090 Screening compound: (2E)-1-{4-[6-(4-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one
M130-1090 Screening compound: (2E)-1-{4-[6-(4-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M130-1090
(2E)-1-{4-[6-(4-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M130-1090

Molecular Formula

C24H24N4O (C24 H24 N4 O)

Compound Name

(2E)-1-{4-[6-(4-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

IUPAC name

(2E)-1-{4-[6-(4-methylphenyl)pyrimidin-4-yl]piperazin-1-yl}-3-phenylprop-2-en-1-one

SMILES

Cc(cc1)ccc1-c1cc(N(CC2)CCN2C(/C=C/c2ccccc2)=O)ncn1

InChI

InChI=1S/C24H24N4O/c1-19-7-10-21(11-8-19)22-17-23(26-18-25-22)27-13-15-28(16-14-27)24(29)12-9-20-5-3-2-4-6-20/h2-12,17-18H,13-16H2,1H3

InChI Key

KTRMFQGFGLIJCF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15141120

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.129

Distribution Coefficient, logD

5.114

Water Solubility, LogSw

-5.07

Polar Surface Area

38.621

Acid Dissociation Constant (pKa)

23.39

Base Dissociation Constant (pKb)

5.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

M130-1090 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with M130-1090 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M130-1090?
Check Price and Availability of M130-1090, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M130-1090 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M130-1090
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M130-1090
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M130-1090 available by request