M131-0946 Screening compound: 4-[4-(3,4-dimethylbenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

M131-0946 Screening compound: 4-[4-(3,4-dimethylbenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine
M131-0946 Screening compound: 4-[4-(3,4-dimethylbenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M131-0946
4-[4-(3,4-dimethylbenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M131-0946

Molecular Formula

C24H26N4O (C24 H26 N4 O)

Compound Name

4-[4-(3,4-dimethylbenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

IUPAC name

4-[4-(34-dimethylbenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

SMILES

Cc(cc1)ccc1-c1nccc(N(CC2)CCN2C(c2cc(C)c(C)cc2)=O)n1

InChI

InChI=1S/C24H26N4O/c1-17-4-7-20(8-5-17)23-25-11-10-22(26-23)27-12-14-28(15-13-27)24(29)21-9-6-18(2)19(3)16-21/h4-11,16H,12-15H2,1-3H3

InChI Key

MNQJQTBRFRTYFN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498593

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.904

Distribution Coefficient, logD

4.882

Water Solubility, LogSw

-4.62

Polar Surface Area

38.342

Acid Dissociation Constant (pKa)

23.23

Base Dissociation Constant (pKb)

6.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

M131-0946 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M131-0946 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M131-0946?
Check Price and Availability of M131-0946, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M131-0946 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M131-0946
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M131-0946
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M131-0946 available by request