M131-1007 Screening compound: 4-[4-(2-chloro-5-fluorobenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

M131-1007 Screening compound: 4-[4-(2-chloro-5-fluorobenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine
M131-1007 Screening compound: 4-[4-(2-chloro-5-fluorobenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M131-1007
4-[4-(2-chloro-5-fluorobenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M131-1007

Molecular Formula

C22H20ClFN4O (C22 H20 ClFN4 O)

Compound Name

4-[4-(2-chloro-5-fluorobenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

IUPAC name

4-[4-(2-chloro-5-fluorobenzoyl)piperazin-1-yl]-2-(4-methylphenyl)pyrimidine

SMILES

Cc(cc1)ccc1-c1nccc(N(CC2)CCN2C(c(cc(cc2)F)c2Cl)=O)n1

InChI

InChI=1S/C22H20ClFN4O/c1-15-2-4-16(5-3-15)21-25-9-8-20(26-21)27-10-12-28(13-11-27)22(29)18-14-17(24)6-7-19(18)23/h2-9,14H,10-13H2,1H3

InChI Key

IEEOKAAWOCZFLZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498595

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.902

Distribution Coefficient, logD

4.881

Water Solubility, LogSw

-4.93

Polar Surface Area

38.342

Acid Dissociation Constant (pKa)

23.23

Base Dissociation Constant (pKb)

6.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

M131-1007 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M131-1007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M131-1007?
Check Price and Availability of M131-1007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M131-1007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M131-1007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M131-1007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M131-1007 available by request