M131-1352 Screening compound: 2-(3-fluorophenyl)-4-{4-[4-(propan-2-yl)benzoyl]piperazin-1-yl}pyrimidine

M131-1352 Screening compound: 2-(3-fluorophenyl)-4-{4-[4-(propan-2-yl)benzoyl]piperazin-1-yl}pyrimidine
M131-1352 Screening compound: 2-(3-fluorophenyl)-4-{4-[4-(propan-2-yl)benzoyl]piperazin-1-yl}pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M131-1352
2-(3-fluorophenyl)-4-{4-[4-(propan-2-yl)benzoyl]piperazin-1-yl}pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M131-1352

Molecular Formula

C24H25FN4O (C24 H25 FN4 O)

Compound Name

2-(3-fluorophenyl)-4-{4-[4-(propan-2-yl)benzoyl]piperazin-1-yl}pyrimidine

IUPAC name

2-(3-fluorophenyl)-4-{4-[4-(propan-2-yl)benzoyl]piperazin-1-yl}pyrimidine

SMILES

CC(C)c(cc1)ccc1C(N(CC1)CCN1c1ccnc(-c2cccc(F)c2)n1)=O

InChI

InChI=1S/C24H25FN4O/c1-17(2)18-6-8-19(9-7-18)24(30)29-14-12-28(13-15-29)22-10-11-26-23(27-22)20-4-3-5-21(25)16-20/h3-11,16-17H,12-15H2,1-2H3

InChI Key

WQYRWOHBSSMWRB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498599

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.038

Distribution Coefficient, logD

5.035

Water Solubility, LogSw

-4.78

Polar Surface Area

38.342

Acid Dissociation Constant (pKa)

23.23

Base Dissociation Constant (pKb)

5.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

M131-1352 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M131-1352 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M131-1352?
Check Price and Availability of M131-1352, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M131-1352 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M131-1352
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M131-1352
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M131-1352 available by request