M136-0023 Screening compound: 2-[4-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidin-1-yl]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridine

M136-0023 Screening compound: 2-[4-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidin-1-yl]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridine
M136-0023 Screening compound: 2-[4-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidin-1-yl]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound M136-0023
2-[4-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidin-1-yl]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M136-0023

Molecular Formula

C30H29N5O2 (C30 H29 N5 O2)

Compound Name

2-[4-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidin-1-yl]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridine

IUPAC name

2-[4-(4-phenyl-1236-tetrahydropyridine-1-carbonyl)piperidin-1-yl]-3-(3-phenyl-124-oxadiazol-5-yl)pyridine

SMILES

O=C(C(CC1)CCN1c1ncccc1-c1nc(-c2ccccc2)no1)N(CC1)CC=C1c1ccccc1

InChI

InChI=1S/C30H29N5O2/c36-30(35-20-13-23(14-21-35)22-8-3-1-4-9-22)25-15-18-34(19-16-25)28-26(12-7-17-31-28)29-32-27(33-37-29)24-10-5-2-6-11-24/h1-13,17,25H,14-16,18-21H2

InChI Key

UGJZQJCQRAABGC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498620

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.818

Distribution Coefficient, logD

5.808

Water Solubility, LogSw

-5.89

Polar Surface Area

60.454

Acid Dissociation Constant (pKa)

22.10

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

M136-0023 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M136-0023 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M136-0023?
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What is the minimum amount of M136-0023 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M136-0023
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M136-0023
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M136-0023 available by request