M136-0174 Screening compound: 3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyridine

M136-0174 Screening compound: 3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyridine
M136-0174 Screening compound: 3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound M136-0174
3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M136-0174

Molecular Formula

C25H29N5O2 (C25 H29 N5 O2)

Compound Name

3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyridine

IUPAC name

3-[3-(3-methylphenyl)-124-oxadiazol-5-yl]-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]pyridine

SMILES

Cc1cccc(-c2noc(-c3cccnc3N(CC3)CCC3C(N3CCCCC3)=O)n2)c1

InChI

InChI=1S/C25H29N5O2/c1-18-7-5-8-20(17-18)22-27-24(32-28-22)21-9-6-12-26-23(21)29-15-10-19(11-16-29)25(31)30-13-3-2-4-14-30/h5-9,12,17,19H,2-4,10-11,13-16H2,1H3

InChI Key

AJYPBSZRZWFQEX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22385981

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.776

Distribution Coefficient, logD

4.766

Water Solubility, LogSw

-4.48

Polar Surface Area

60.726

Acid Dissociation Constant (pKa)

22.10

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

M136-0174 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M136-0174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M136-0174?
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What is the minimum amount of M136-0174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M136-0174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M136-0174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M136-0174 available by request