M136-0215 Screening compound: 1-[4-(1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carbonyl)piperazin-1-yl]ethan-1-one

M136-0215 Screening compound: 1-[4-(1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carbonyl)piperazin-1-yl]ethan-1-one
M136-0215 Screening compound: 1-[4-(1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carbonyl)piperazin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M136-0215
1-[4-(1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carbonyl)piperazin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M136-0215

Molecular Formula

C25H27FN6O3 (C25 H27 FN6 O3)

Compound Name

1-[4-(1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carbonyl)piperazin-1-yl]ethan-1-one

IUPAC name

1-[4-(1-{3-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carbonyl)piperazin-1-yl]ethan-1-one

SMILES

CC(N(CC1)CCN1C(C(CC1)CCN1c(nccc1)c1-c1nc(-c2cccc(F)c2)no1)=O)=O

InChI

InChI=1S/C25H27FN6O3/c1-17(33)30-12-14-32(15-13-30)25(34)18-7-10-31(11-8-18)23-21(6-3-9-27-23)24-28-22(29-35-24)19-4-2-5-20(26)16-19/h2-6,9,16,18H,7-8,10-15H2,1H3

InChI Key

SCIPHAKYMAHAMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27498635

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.170

Distribution Coefficient, logD

3.160

Water Solubility, LogSw

-3.23

Polar Surface Area

77.921

Acid Dissociation Constant (pKa)

22.10

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

M136-0215 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with M136-0215 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M136-0215?
Check Price and Availability of M136-0215, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M136-0215 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M136-0215
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M136-0215
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M136-0215 available by request