M136-0348 Screening compound: 1-{3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-cyclohexylpiperidine-4-carboxamide

M136-0348 Screening compound: 1-{3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-cyclohexylpiperidine-4-carboxamide
M136-0348 Screening compound: 1-{3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-cyclohexylpiperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M136-0348
1-{3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-cyclohexylpiperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M136-0348

Molecular Formula

C25H28ClN5O2 (C25 H28 ClN5 O2)

Compound Name

1-{3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-cyclohexylpiperidine-4-carboxamide

IUPAC name

1-{3-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]pyridin-2-yl}-N-cyclohexylpiperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(nccc1)c1-c1nc(-c(cc2)ccc2Cl)no1)NC1CCCCC1

InChI

InChI=1S/C25H28ClN5O2/c26-19-10-8-17(9-11-19)22-29-25(33-30-22)21-7-4-14-27-23(21)31-15-12-18(13-16-31)24(32)28-20-5-2-1-3-6-20/h4,7-11,14,18,20H,1-3,5-6,12-13,15-16H2,(H,28,32)

InChI Key

CVRFJXBQHALPFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532119

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.98

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.539

Distribution Coefficient, logD

5.529

Water Solubility, LogSw

-6.05

Polar Surface Area

68.216

Acid Dissociation Constant (pKa)

15.04

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

M136-0348 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with M136-0348 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M136-0348?
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What is the minimum amount of M136-0348 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M136-0348
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M136-0348
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M136-0348 available by request