M136-0583 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carboxamide

M136-0583 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carboxamide
M136-0583 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M136-0583
N-(2,3-dihydro-1H-inden-1-yl)-1-{3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M136-0583

Molecular Formula

C29H29N5O2 (C29 H29 N5 O2)

Compound Name

N-(2,3-dihydro-1H-inden-1-yl)-1-{3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carboxamide

IUPAC name

N-(23-dihydro-1H-inden-1-yl)-1-{3-[3-(4-methylphenyl)-124-oxadiazol-5-yl]pyridin-2-yl}piperidine-4-carboxamide

SMILES

Cc(cc1)ccc1-c1noc(-c2cccnc2N(CC2)CCC2C(NC(CC2)c3c2cccc3)=O)n1

InChI

InChI=1S/C29H29N5O2/c1-19-8-10-21(11-9-19)26-32-29(36-33-26)24-7-4-16-30-27(24)34-17-14-22(15-18-34)28(35)31-25-13-12-20-5-2-3-6-23(20)25/h2-11,16,22,25H,12-15,17-18H2,1H3,(H,31,35)/t25-/m0/s1

InChI Key

DCXBYQCMHSHMDM-VWLOTQADSA-N

MDL Number (MFCD)

MFCD27532147

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.582

Distribution Coefficient, logD

5.571

Water Solubility, LogSw

-5.32

Polar Surface Area

68.701

Acid Dissociation Constant (pKa)

12.08

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.00

M136-0583 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Structure:
  • Mimetics
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with M136-0583 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M136-0583?
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What is the minimum amount of M136-0583 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M136-0583
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M136-0583
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M136-0583 available by request