M136-0632 Screening compound: 1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

Chemical Structure Depiction of ChemDiv screening compound M136-0632
1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

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Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M136-0632

Molecular Formula

C₂₅H₂₃ClN₆O₂ (C25 H23 ClN6 O2)

Compound Name

1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-{3-[3-(3-chlorophenyl)-124-oxadiazol-5-yl]pyridin-2-yl}-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(nccc1)c1-c1nc(-c2cccc(Cl)c2)no1)NCc1ncccc1

InChI

InChI=1S/C25H23ClN6O2/c26-19-6-3-5-18(15-19)22-30-25(34-31-22)21-8-4-12-28-23(21)32-13-9-17(10-14-32)24(33)29-16-20-7-1-2-11-27-20/h1-8,11-12,15,17H,9-10,13-14,16H2,(H,29,33)

InChI Key

GVYDCFILROSWCD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20739272

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.95

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

4.245

Distribution Coefficient, logD

4.235

Water Solubility, LogSw

-4.50

Polar Surface Area

78.034

Acid Dissociation Constant (pK_a)

12.37

Base Dissociation Constant (pK_b)

5.77

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

24.00

M136-0632 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Nervous system
Cancer
Digestive system
Respiratory tract
Male
Female
Hemic and lymphatic
Immune system
Hemic and lymphatic
Cardiovascular
Infections
Cancer
Musculoskeletal
Digestive system
Respiratory tract
Male
Female
Cardiovascular
Skin
Metabolic
Immune system
Cancer
Digestive system
Respiratory tract
Nervous system
Eye
Cardiovascular

Mechanism of action:

PPI modulators
PPI modulators
Receptor's ligands

Structure:

Mimetics

Targets:

Proteases
GPCR

References: we are preparing a list of scientific research reports with M136-0632 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M136-0632?
Check Price and Availability of M136-0632, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of M136-0632 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for M136-0632
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for M136-0632

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M136-0632 available by request