M136-0641 Screening compound: 1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[3-(propan-2-yloxy)propyl]piperidine-4-carboxamide

M136-0641 Screening compound: 1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[3-(propan-2-yloxy)propyl]piperidine-4-carboxamide
M136-0641 Screening compound: 1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[3-(propan-2-yloxy)propyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M136-0641
1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[3-(propan-2-yloxy)propyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M136-0641

Molecular Formula

C25H30ClN5O3 (C25 H30 ClN5 O3)

Compound Name

1-{3-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-N-[3-(propan-2-yloxy)propyl]piperidine-4-carboxamide

IUPAC name

1-{3-[3-(3-chlorophenyl)-124-oxadiazol-5-yl]pyridin-2-yl}-N-[3-(propan-2-yloxy)propyl]piperidine-4-carboxamide

SMILES

CC(C)OCCCNC(C(CC1)CCN1c(nccc1)c1-c1nc(-c2cccc(Cl)c2)no1)=O

InChI

InChI=1S/C25H30ClN5O3/c1-17(2)33-15-5-12-28-24(32)18-9-13-31(14-10-18)23-21(8-4-11-27-23)25-29-22(30-34-25)19-6-3-7-20(26)16-19/h3-4,6-8,11,16-18H,5,9-10,12-15H2,1-2H3,(H,28,32)

InChI Key

LXGGZOXZCLVIPX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532164

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.561

Distribution Coefficient, logD

4.551

Water Solubility, LogSw

-4.62

Polar Surface Area

75.805

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

M136-0641 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Structure:
  • Mimetics
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with M136-0641 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M136-0641?
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What is the minimum amount of M136-0641 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M136-0641
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M136-0641
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M136-0641 available by request