M143-0061 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-({7-methylpyrimido[4,5-d][1,3]diazin-4-yl}sulfanyl)acetamide

M143-0061 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-({7-methylpyrimido[4,5-d][1,3]diazin-4-yl}sulfanyl)acetamide
M143-0061 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-({7-methylpyrimido[4,5-d][1,3]diazin-4-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M143-0061
N-(5-chloro-2,4-dimethoxyphenyl)-2-({7-methylpyrimido[4,5-d][1,3]diazin-4-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M143-0061

Molecular Formula

C17H16ClN5O3S (C17 H16 ClN5 O3 S)

Compound Name

N-(5-chloro-2,4-dimethoxyphenyl)-2-({7-methylpyrimido[4,5-d][1,3]diazin-4-yl}sulfanyl)acetamide

IUPAC name

N-(5-chloro-24-dimethoxyphenyl)-2-({7-methylpyrimido[45-d][13]diazin-4-yl}sulfanyl)acetamide

SMILES

Cc1ncc2c(SCC(Nc(c(OC)c3)cc(Cl)c3OC)=O)ncnc2n1

InChI

InChI=1S/C17H16ClN5O3S/c1-9-19-6-10-16(22-9)20-8-21-17(10)27-7-15(24)23-12-4-11(18)13(25-2)5-14(12)26-3/h4-6,8H,7H2,1-3H3,(H,23,24)

InChI Key

SOCXIRNOOUDKIX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20736510

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.86

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.439

Distribution Coefficient, logD

2.431

Water Solubility, LogSw

-3.11

Polar Surface Area

77.368

Acid Dissociation Constant (pKa)

9.12

Base Dissociation Constant (pKb)

2.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

M143-0061 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M143-0061 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M143-0061?
Check Price and Availability of M143-0061, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M143-0061 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M143-0061
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M143-0061
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M143-0061 available by request