M143-0596 Screening compound: ethyl 4-(2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamido)benzoate

M143-0596 Screening compound: ethyl 4-(2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamido)benzoate
M143-0596 Screening compound: ethyl 4-(2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound M143-0596
ethyl 4-(2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M143-0596

Molecular Formula

C24H21N5O4S (C24 H21 N5 O4 S)

Compound Name

ethyl 4-(2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamido)benzoate

IUPAC name

ethyl 4-(2-{[7-(4-methoxyphenyl)pyrimido[45-d][13]diazin-4-yl]sulfanyl}acetamido)benzoate

SMILES

CCOC(c(cc1)ccc1NC(CSc1ncnc2nc(-c(cc3)ccc3OC)ncc12)=O)=O

InChI

InChI=1S/C24H21N5O4S/c1-3-33-24(31)16-4-8-17(9-5-16)28-20(30)13-34-23-19-12-25-21(29-22(19)26-14-27-23)15-6-10-18(32-2)11-7-15/h4-12,14H,3,13H2,1-2H3,(H,28,30)

InChI Key

MCHSTZWCMLUJJG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532288

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.53

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.622

Distribution Coefficient, logD

4.621

Water Solubility, LogSw

-4.10

Polar Surface Area

91.218

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

M143-0596 in Drug Discovery

Included in Screening Libraries

ACE2 Library (3043 compounds)

CORONAVIRUS Library (20774 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M143-0596 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M143-0596?
Check Price and Availability of M143-0596, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M143-0596 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M143-0596
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M143-0596
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M143-0596 available by request