M143-0696 Screening compound: N-[(2-bromophenyl)methyl]-2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamide

M143-0696 Screening compound: N-[(2-bromophenyl)methyl]-2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamide
M143-0696 Screening compound: N-[(2-bromophenyl)methyl]-2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M143-0696
N-[(2-bromophenyl)methyl]-2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M143-0696

Molecular Formula

C22H18BrN5O2S (C22 H18 BrN5 O2 S)

Compound Name

N-[(2-bromophenyl)methyl]-2-{[7-(4-methoxyphenyl)pyrimido[4,5-d][1,3]diazin-4-yl]sulfanyl}acetamide

IUPAC name

N-[(2-bromophenyl)methyl]-2-{[7-(4-methoxyphenyl)pyrimido[45-d][13]diazin-4-yl]sulfanyl}acetamide

SMILES

COc(cc1)ccc1-c1ncc2c(SCC(NCc(cccc3)c3Br)=O)ncnc2n1

InChI

InChI=1S/C22H18BrN5O2S/c1-30-16-8-6-14(7-9-16)20-25-11-17-21(28-20)26-13-27-22(17)31-12-19(29)24-10-15-4-2-3-5-18(15)23/h2-9,11,13H,10,12H2,1H3,(H,24,29)

InChI Key

QLHSDQSLZNFLFY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532315

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.573

Distribution Coefficient, logD

4.573

Water Solubility, LogSw

-4.21

Polar Surface Area

71.786

Acid Dissociation Constant (pKa)

13.26

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

M143-0696 in Drug Discovery

Included in Screening Libraries

ACE2 Library (3043 compounds)

CORONAVIRUS Library (20774 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M143-0696 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M143-0696?
Check Price and Availability of M143-0696, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M143-0696 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M143-0696
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M143-0696
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M143-0696 available by request