M144-1177 Screening compound: 1-phenyl-4-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperazine

M144-1177 Screening compound: 1-phenyl-4-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperazine
M144-1177 Screening compound: 1-phenyl-4-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound M144-1177
1-phenyl-4-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M144-1177

Molecular Formula

C25H29N5O3S (C25 H29 N5 O3 S)

Compound Name

1-phenyl-4-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperazine

IUPAC name

1-phenyl-4-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperazine

SMILES

O=C(c(nc1)cn1-c(cc1)ccc1S(N1CCCCC1)(=O)=O)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C25H29N5O3S/c31-25(28-17-15-27(16-18-28)21-7-3-1-4-8-21)24-19-29(20-26-24)22-9-11-23(12-10-22)34(32,33)30-13-5-2-6-14-30/h1,3-4,7-12,19-20H,2,5-6,13-18H2

InChI Key

VWFRKKYGWLHRJV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532419

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.362

Distribution Coefficient, logD

3.362

Water Solubility, LogSw

-3.50

Polar Surface Area

64.096

Acid Dissociation Constant (pKa)

28.03

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

M144-1177 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M144-1177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M144-1177?
Check Price and Availability of M144-1177, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M144-1177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M144-1177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M144-1177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M144-1177 available by request