M144-1182 Screening compound: ethyl 1-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperidine-3-carboxylate

M144-1182 Screening compound: ethyl 1-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperidine-3-carboxylate
M144-1182 Screening compound: ethyl 1-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperidine-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound M144-1182
ethyl 1-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperidine-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M144-1182

Molecular Formula

C23H30N4O5S (C23 H30 N4 O5 S)

Compound Name

ethyl 1-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperidine-3-carboxylate

IUPAC name

ethyl 1-{1-[4-(piperidine-1-sulfonyl)phenyl]-1H-imidazole-4-carbonyl}piperidine-3-carboxylate

SMILES

CCOC(C(CCC1)CN1C(c(nc1)cn1-c(cc1)ccc1S(N1CCCCC1)(=O)=O)=O)=O

InChI

InChI=1S/C23H30N4O5S/c1-2-32-23(29)18-7-6-12-25(15-18)22(28)21-16-26(17-24-21)19-8-10-20(11-9-19)33(30,31)27-13-4-3-5-14-27/h8-11,16-18H,2-7,12-15H2,1H3/t18-/m0/s1

InChI Key

JAXSJQDSBCTPMP-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27532421

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.676

Distribution Coefficient, logD

2.676

Water Solubility, LogSw

-2.73

Polar Surface Area

81.523

Acid Dissociation Constant (pKa)

22.52

Base Dissociation Constant (pKb)

1.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.20

M144-1182 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M144-1182 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M144-1182?
Check Price and Availability of M144-1182, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M144-1182 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M144-1182
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M144-1182
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M144-1182 available by request