M144-1597 Screening compound: 4-(4-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-imidazol-1-yl}benzenesulfonyl)morpholine

M144-1597 Screening compound: 4-(4-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-imidazol-1-yl}benzenesulfonyl)morpholine
M144-1597 Screening compound: 4-(4-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-imidazol-1-yl}benzenesulfonyl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound M144-1597
4-(4-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-imidazol-1-yl}benzenesulfonyl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M144-1597

Molecular Formula

C23H26N6O4S (C23 H26 N6 O4 S)

Compound Name

4-(4-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-imidazol-1-yl}benzenesulfonyl)morpholine

IUPAC name

4-(4-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-imidazol-1-yl}benzenesulfonyl)morpholine

SMILES

O=C(c(nc1)cn1-c(cc1)ccc1S(N1CCOCC1)(=O)=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C23H26N6O4S/c30-23(27-11-9-26(10-12-27)22-3-1-2-8-24-22)21-17-28(18-25-21)19-4-6-20(7-5-19)34(31,32)29-13-15-33-16-14-29/h1-8,17-18H,9-16H2

InChI Key

PLVZIGCPCLCVIF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.56

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.040

Distribution Coefficient, logD

2.032

Water Solubility, LogSw

-2.29

Polar Surface Area

80.516

Acid Dissociation Constant (pKa)

24.77

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

M144-1597 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M144-1597 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M144-1597?
Check Price and Availability of M144-1597, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M144-1597 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M144-1597
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M144-1597
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M144-1597 available by request