M146-1794 Screening compound: 2-[(4-methoxyphenoxy)methyl]-N~5~-[(1S)-1-methylpropyl]-4-(4-pyridyl)-5-pyrimidinecarboxamide

M146-1794 Screening compound: 2-[(4-methoxyphenoxy)methyl]-N~5~-[(1S)-1-methylpropyl]-4-(4-pyridyl)-5-pyrimidinecarboxamide
M146-1794 Screening compound: 2-[(4-methoxyphenoxy)methyl]-N~5~-[(1S)-1-methylpropyl]-4-(4-pyridyl)-5-pyrimidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M146-1794
2-[(4-methoxyphenoxy)methyl]-N~5~-[(1S)-1-methylpropyl]-4-(4-pyridyl)-5-pyrimidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M146-1794

Molecular Formula

C22H24N4O3 (C22 H24 N4 O3)

Compound Name

2-[(4-methoxyphenoxy)methyl]-N~5~-[(1S)-1-methylpropyl]-4-(4-pyridyl)-5-pyrimidinecarboxamide

IUPAC name

n/a

SMILES

CCC(C)NC(c1c(-c2ccncc2)nc(COc(cc2)ccc2OC)nc1)=O

InChI

InChI=1S/C22H24N4O3/c1-4-15(2)25-22(27)19-13-24-20(26-21(19)16-9-11-23-12-10-16)14-29-18-7-5-17(28-3)6-8-18/h5-13,15H,4,14H2,1-3H3,(H,25,27)/t15-/m0/s1

InChI Key

GWNIOMNJHLPNRJ-HNNXBMFYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.636

Distribution Coefficient, logD

2.636

Water Solubility, LogSw

-2.59

Polar Surface Area

69.147

Acid Dissociation Constant (pKa)

14.66

Base Dissociation Constant (pKb)

4.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

M146-1794 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with M146-1794 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M146-1794?
Check Price and Availability of M146-1794, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M146-1794 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M146-1794
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M146-1794
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M146-1794 available by request