M148-6659 Screening compound: 2-[4-(4-chlorophenyl)-3-(morpholin-4-yl)-1H-pyrazol-1-yl]-N-(3-methylphenyl)acetamide

M148-6659 Screening compound: 2-[4-(4-chlorophenyl)-3-(morpholin-4-yl)-1H-pyrazol-1-yl]-N-(3-methylphenyl)acetamide
M148-6659 Screening compound: 2-[4-(4-chlorophenyl)-3-(morpholin-4-yl)-1H-pyrazol-1-yl]-N-(3-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M148-6659
2-[4-(4-chlorophenyl)-3-(morpholin-4-yl)-1H-pyrazol-1-yl]-N-(3-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M148-6659

Molecular Formula

C22H23ClN4O2 (C22 H23 ClN4 O2)

Compound Name

2-[4-(4-chlorophenyl)-3-(morpholin-4-yl)-1H-pyrazol-1-yl]-N-(3-methylphenyl)acetamide

IUPAC name

2-[4-(4-chlorophenyl)-3-(morpholin-4-yl)-1H-pyrazol-1-yl]-N-(3-methylphenyl)acetamide

SMILES

Cc1cccc(NC(Cn(cc2-c(cc3)ccc3Cl)nc2N2CCOCC2)=O)c1

InChI

InChI=1S/C22H23ClN4O2/c1-16-3-2-4-19(13-16)24-21(28)15-27-14-20(17-5-7-18(23)8-6-17)22(25-27)26-9-11-29-12-10-26/h2-8,13-14H,9-12,15H2,1H3,(H,24,28)

InChI Key

LMYGBHCKSUZNBH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532637

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.686

Distribution Coefficient, logD

4.686

Water Solubility, LogSw

-4.76

Polar Surface Area

48.692

Acid Dissociation Constant (pKa)

12.95

Base Dissociation Constant (pKb)

1.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

M148-6659 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with M148-6659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M148-6659?
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What is the minimum amount of M148-6659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M148-6659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M148-6659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M148-6659 available by request