M148-8427 Screening compound: 2-[3-(dimethylamino)-4-(4-methoxyphenyl)-1H-pyrazol-1-yl]-N-{[4-(trifluoromethyl)phenyl]methyl}acetamide

M148-8427 Screening compound: 2-[3-(dimethylamino)-4-(4-methoxyphenyl)-1H-pyrazol-1-yl]-N-{[4-(trifluoromethyl)phenyl]methyl}acetamide
M148-8427 Screening compound: 2-[3-(dimethylamino)-4-(4-methoxyphenyl)-1H-pyrazol-1-yl]-N-{[4-(trifluoromethyl)phenyl]methyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M148-8427
2-[3-(dimethylamino)-4-(4-methoxyphenyl)-1H-pyrazol-1-yl]-N-{[4-(trifluoromethyl)phenyl]methyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M148-8427

Molecular Formula

C22H23F3N4O2 (C22 H23 F3 N4 O2)

Compound Name

2-[3-(dimethylamino)-4-(4-methoxyphenyl)-1H-pyrazol-1-yl]-N-{[4-(trifluoromethyl)phenyl]methyl}acetamide

IUPAC name

2-[3-(dimethylamino)-4-(4-methoxyphenyl)-1H-pyrazol-1-yl]-N-{[4-(trifluoromethyl)phenyl]methyl}acetamide

SMILES

CN(C)c1nn(CC(NCc2ccc(C(F)(F)F)cc2)=O)cc1-c(cc1)ccc1OC

InChI

InChI=1S/C22H23F3N4O2/c1-28(2)21-19(16-6-10-18(31-3)11-7-16)13-29(27-21)14-20(30)26-12-15-4-8-17(9-5-15)22(23,24)25/h4-11,13H,12,14H2,1-3H3,(H,26,30)

InChI Key

KHPMGROUCIMJLD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22598323

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.155

Distribution Coefficient, logD

4.155

Water Solubility, LogSw

-4.16

Polar Surface Area

49.002

Acid Dissociation Constant (pKa)

13.26

Base Dissociation Constant (pKb)

1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

M148-8427 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M148-8427 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M148-8427?
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What is the minimum amount of M148-8427 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M148-8427
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M148-8427
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M148-8427 available by request