M148-8475 Screening compound: 2-[3-(dimethylamino)-4-(4-fluorophenyl)-1H-pyrazol-1-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

M148-8475 Screening compound: 2-[3-(dimethylamino)-4-(4-fluorophenyl)-1H-pyrazol-1-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one
M148-8475 Screening compound: 2-[3-(dimethylamino)-4-(4-fluorophenyl)-1H-pyrazol-1-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M148-8475
2-[3-(dimethylamino)-4-(4-fluorophenyl)-1H-pyrazol-1-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M148-8475

Molecular Formula

C23H26FN5O (C23 H26 FN5 O)

Compound Name

2-[3-(dimethylamino)-4-(4-fluorophenyl)-1H-pyrazol-1-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

IUPAC name

2-[3-(dimethylamino)-4-(4-fluorophenyl)-1H-pyrazol-1-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

SMILES

CN(C)c1nn(CC(N(CC2)CCN2c2ccccc2)=O)cc1-c(cc1)ccc1F

InChI

InChI=1S/C23H26FN5O/c1-26(2)23-21(18-8-10-19(24)11-9-18)16-29(25-23)17-22(30)28-14-12-27(13-15-28)20-6-4-3-5-7-20/h3-11,16H,12-15,17H2,1-2H3

InChI Key

RQQGRBYMLRZBBO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642605

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.49

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.195

Distribution Coefficient, logD

3.195

Water Solubility, LogSw

-3.29

Polar Surface Area

36.639

Acid Dissociation Constant (pKa)

25.71

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

M148-8475 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with M148-8475 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M148-8475?
Check Price and Availability of M148-8475, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M148-8475 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M148-8475
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M148-8475
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M148-8475 available by request