M151-0445 Screening compound: 2-(dimethylamino)-3-(4-fluorophenyl)-N-[(furan-2-yl)methyl]-3H-thieno[2,3-d]imidazole-5-carboxamide

M151-0445 Screening compound: 2-(dimethylamino)-3-(4-fluorophenyl)-N-[(furan-2-yl)methyl]-3H-thieno[2,3-d]imidazole-5-carboxamide
M151-0445 Screening compound: 2-(dimethylamino)-3-(4-fluorophenyl)-N-[(furan-2-yl)methyl]-3H-thieno[2,3-d]imidazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M151-0445
2-(dimethylamino)-3-(4-fluorophenyl)-N-[(furan-2-yl)methyl]-3H-thieno[2,3-d]imidazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M151-0445

Molecular Formula

C19H17FN4O2S (C19 H17 FN4 O2 S)

Compound Name

2-(dimethylamino)-3-(4-fluorophenyl)-N-[(furan-2-yl)methyl]-3H-thieno[2,3-d]imidazole-5-carboxamide

IUPAC name

2-(dimethylamino)-3-(4-fluorophenyl)-N-[(furan-2-yl)methyl]-3H-thieno[23-d]imidazole-5-carboxamide

SMILES

CN(C)c(n1-c(cc2)ccc2F)nc2c1sc(C(NCc1ccco1)=O)c2

InChI

InChI=1S/C19H17FN4O2S/c1-23(2)19-22-15-10-16(17(25)21-11-14-4-3-9-26-14)27-18(15)24(19)13-7-5-12(20)6-8-13/h3-10H,11H2,1-2H3,(H,21,25)

InChI Key

ANUMZTTYRAAANO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27532723

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.152

Distribution Coefficient, logD

4.082

Water Solubility, LogSw

-4.22

Polar Surface Area

46.271

Acid Dissociation Constant (pKa)

12.01

Base Dissociation Constant (pKb)

6.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

M151-0445 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Proteases
  • Others

References: we are preparing a list of scientific research reports with M151-0445 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M151-0445?
Check Price and Availability of M151-0445, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M151-0445 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M151-0445
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M151-0445
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M151-0445 available by request