M183-0018 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-2-[4-(dimethylamino)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide

M183-0018 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-2-[4-(dimethylamino)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide
M183-0018 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-2-[4-(dimethylamino)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M183-0018
N-(2H-1,3-benzodioxol-5-yl)-2-[4-(dimethylamino)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M183-0018

Molecular Formula

C19H18N4O4 (C19 H18 N4 O4)

Compound Name

N-(2H-1,3-benzodioxol-5-yl)-2-[4-(dimethylamino)-1-oxo-1,2-dihydrophthalazin-2-yl]acetamide

IUPAC name

N-(2H-13-benzodioxol-5-yl)-2-[4-(dimethylamino)-1-oxo-12-dihydrophthalazin-2-yl]acetamide

SMILES

CN(C)C(c1c2cccc1)=NN(CC(Nc(cc1)cc3c1OCO3)=O)C2=O

InChI

InChI=1S/C19H18N4O4/c1-22(2)18-13-5-3-4-6-14(13)19(25)23(21-18)10-17(24)20-12-7-8-15-16(9-12)27-11-26-15/h3-9H,10-11H2,1-2H3,(H,20,24)

InChI Key

BMXYVWRFHARDGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15141187

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.859

Distribution Coefficient, logD

1.859

Water Solubility, LogSw

-2.98

Polar Surface Area

69.854

Acid Dissociation Constant (pKa)

11.83

Base Dissociation Constant (pKb)

1.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

M183-0018 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M183-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M183-0018?
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What is the minimum amount of M183-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M183-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M183-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M183-0018 available by request