M183-0560 Screening compound: 4-(morpholin-4-yl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,2-dihydrophthalazin-1-one

M183-0560 Screening compound: 4-(morpholin-4-yl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,2-dihydrophthalazin-1-one
M183-0560 Screening compound: 4-(morpholin-4-yl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,2-dihydrophthalazin-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M183-0560
4-(morpholin-4-yl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,2-dihydrophthalazin-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M183-0560

Molecular Formula

C24H27N5O3 (C24 H27 N5 O3)

Compound Name

4-(morpholin-4-yl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,2-dihydrophthalazin-1-one

IUPAC name

4-(morpholin-4-yl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-12-dihydrophthalazin-1-one

SMILES

O=C(CN(C(c1c2cccc1)=O)N=C2N1CCOCC1)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C24H27N5O3/c30-22(27-12-10-26(11-13-27)19-6-2-1-3-7-19)18-29-24(31)21-9-5-4-8-20(21)23(25-29)28-14-16-32-17-15-28/h1-9H,10-18H2

InChI Key

OUXAMIMTSVPBBS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27533854

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.539

Distribution Coefficient, logD

1.539

Water Solubility, LogSw

-2.36

Polar Surface Area

57.798

Acid Dissociation Constant (pKa)

18.30

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

M183-0560 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with M183-0560 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M183-0560?
Check Price and Availability of M183-0560, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M183-0560 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M183-0560
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M183-0560
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M183-0560 available by request