M183-0838 Screening compound: 2-[4-(azepan-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-(2-ethyl-6-methylphenyl)acetamide

M183-0838 Screening compound: 2-[4-(azepan-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-(2-ethyl-6-methylphenyl)acetamide
M183-0838 Screening compound: 2-[4-(azepan-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-(2-ethyl-6-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M183-0838
2-[4-(azepan-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-(2-ethyl-6-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M183-0838

Molecular Formula

C25H30N4O2 (C25 H30 N4 O2)

Compound Name

2-[4-(azepan-1-yl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-(2-ethyl-6-methylphenyl)acetamide

IUPAC name

2-[4-(azepan-1-yl)-1-oxo-12-dihydrophthalazin-2-yl]-N-(2-ethyl-6-methylphenyl)acetamide

SMILES

CCc(cccc1C)c1NC(CN(C(c1c2cccc1)=O)N=C2N1CCCCCC1)=O

InChI

InChI=1S/C25H30N4O2/c1-3-19-12-10-11-18(2)23(19)26-22(30)17-29-25(31)21-14-7-6-13-20(21)24(27-29)28-15-8-4-5-9-16-28/h6-7,10-14H,3-5,8-9,15-17H2,1-2H3,(H,26,30)

InChI Key

CGEOVZHZVKPFAI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27533881

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.277

Distribution Coefficient, logD

4.277

Water Solubility, LogSw

-4.12

Polar Surface Area

52.322

Acid Dissociation Constant (pKa)

13.11

Base Dissociation Constant (pKb)

1.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

M183-0838 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with M183-0838 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M183-0838?
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What is the minimum amount of M183-0838 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M183-0838
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M183-0838
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M183-0838 available by request