M183-1245 Screening compound: 2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-(4-methylpiperidin-1-yl)-1,2-dihydrophthalazin-1-one

M183-1245 Screening compound: 2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-(4-methylpiperidin-1-yl)-1,2-dihydrophthalazin-1-one
M183-1245 Screening compound: 2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-(4-methylpiperidin-1-yl)-1,2-dihydrophthalazin-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M183-1245
2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-(4-methylpiperidin-1-yl)-1,2-dihydrophthalazin-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M183-1245

Molecular Formula

C26H30FN5O2 (C26 H30 FN5 O2)

Compound Name

2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-(4-methylpiperidin-1-yl)-1,2-dihydrophthalazin-1-one

IUPAC name

2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-(4-methylpiperidin-1-yl)-12-dihydrophthalazin-1-one

SMILES

CC(CC1)CCN1C(c1c2cccc1)=NN(CC(N(CC1)CCN1c(cccc1)c1F)=O)C2=O

InChI

InChI=1S/C26H30FN5O2/c1-19-10-12-31(13-11-19)25-20-6-2-3-7-21(20)26(34)32(28-25)18-24(33)30-16-14-29(15-17-30)23-9-5-4-8-22(23)27/h2-9,19H,10-18H2,1H3

InChI Key

YKOZIRIMTFVKTF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15141259

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.207

Distribution Coefficient, logD

3.207

Water Solubility, LogSw

-3.72

Polar Surface Area

49.589

Acid Dissociation Constant (pKa)

18.30

Base Dissociation Constant (pKb)

4.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

M183-1245 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with M183-1245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M183-1245?
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What is the minimum amount of M183-1245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M183-1245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M183-1245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M183-1245 available by request